Bridget manages the Stem Cell Sorting
laboratory within the UC Davis Institute for Regenerative Cures
in Sacramento, California. After receiving her B.S. in Molecular
Biology from the University of Wyoming, Bridget was offered an
internship with the USDA Arthropod Borne Animal Diseases
Research Lab in Laramie, WY. That internship led to an offer to
pursue a two year graduate program at the University of
California, Davis, with support from a USDA student training
grant. She was introduced to the advantages of flow cytometry
during her graduate training in the UC Davis School of
Veterinary Medicine where she used a
two color approach to assess viral damage to vascular cells in
ruminant animals. After working in the pharmaceutical industry
with genetically engineered oncolytic adenoviruses, she returned
to UC Davis to work under the direction of a team of flow
cytometry experts from around the U.S. to develop standardized 9
color T cell immunophenotyping and cytokine response staining
panels using differently configured cytometers. Through this
work, Bridget developed expertise in multicolor reagent panel
development, antibody conjugation techniques, and cytometer
quality control and she has published manuscripts on reagent
panel development and instrument validation in the journal
Cytometry. Recently, she developed tissue staining and scanning
techniques to identify T cells on the iCys laser scanning
cytometer and provides training on this instrument for
researchers at UC Davis. She has over 10 years of experience in
flow cytometry, fluorescent reagent preparation, multicolor
staining, data analysis and laser scanning cytometry. She has
attended multiple flow cytometry and imaging courses, including
the Dartmouth Clinical Flow Cytometry Course and the
Quantitative Imaging Symposium as well as specialized operator
training courses for the LSRII analyzer, inFlux and Aria II GMP
cell sorters and the iCys laser scanning cytometer.
You can reach Bridget at
bmclaughlin@ucdavis.edu