We are delighted
to welcome Dorothy as a FloCyte Associates, Dorothy teaches our Intracellular
Flow Courses. She grew up in rural Arizona and received her Ph.D in Microbiology in 1978 from the University of
Arizona. In her biophysics class in the mid 70’s she actually first heard about
flow cytometry and its promise. Her Ph.D examined a guinea pig model of Multiple
Sclerosis.
In
1978 she went to Albuquerque New Mexico to do a postdoc on autoimmunity in NZB
mice with Dr. Noel Warner. He trained in Australia with the Nobel Prize winner
MacFarland Burnett and also did a postdoc with the Herzenberg’s of flow fame at
Stanford. It was in New Mexico that Dorothy first had hands on experience in
flow cytometry. First at Los Alamos and then in 1979 the lab in Albuquerque got
a FACS III. This had a dot plot oscilloscope cassette tapes for data storage.
This took forever!
In
1982 she moved to Houston, Texas to set up a flow laboratory and to establish
her own research first on autoimmune disease and then on HIV immune responses.
She bought a Coulter Epics, which would later become a 753, with Cytomation
acquisition. She currently has an ALTRA high pressure cell sorter and 2
analytical XL2 machines. She thus has more than 25 years of flow experience. She
has seen all sorts (no pun intended) of flow applications. Since 1998 she has
taught a flow class for 10-15 students from Baylor College of Medicine and
University of Texas at Houston. She ran a flow facility for both the Center for
AIDS Research and the Dan L. Duncan Cancer Center. Dorothy also has served on
numerous study sections, is chair of a California AIDS Study section, was an NIH
council member from 2002-2006 and is Chair of the Los Alamos National Laboratory
Flow Cytometry advisory committee. She received a merit award from NIAID from
2000-2010 in support of her AIDS research.
In 2008, Dorothy joined the U Texas Medical Branch Galveston, Texas where she is
Professor of Internal Medicine Infectious Disease Division, Professor of
Microbiology and Immunology and Professor of Pathology. She is also Director of
the Galveston National Laboratory Flow Cytometry Facility U Texas Medical Branch
Galveston, Texas! You can reach Dorothy at dolewis@utmb.edu .
She
can be reached at flow@bcm.edu , see website: www.bcm.edu/flow, or telephone at 713-798-6054.