
The Flow Cytometry community recently lost our dear colleague,
Phil Marder who joined FloCyte just briefly in 2008. Phil died
Saturday, January 30th, 2010 after his 14 month battle with brain
cancer. He will be greatly missed!
Phil received his graduate training in microbiology from The Ohio State
University. Upon his graduation, he joined Eli Lilly research labs
as an associate cell biologist. Early in his career, Phil was
given the opportunity to introduce flow cytometry as an enabling
technology for Lilly’s drug discovery platforms. In this hands-on
role, Phil provided his company with the powerful flow
applications of immunophenotypic analysis, calcium mobilization,
DNA cell cycle detection and FACS® cell sorting. During
the late 1980’s, Phil began working with clinical development
teams to incorporate flow cytometric technology into drug activity
biomarker studies of early clinical trials. During the late
1990’s, Phil also helped introduce the breakthrough technology of
multiplexed analyte detection (Luminex - xMAP®) to
Lilly. Phil’s vision of using flow cytometric analysis to uncover
pharmacodynamic effects on the surrogate target cells in blood
proved to be a boon for Lilly’s drug development processes. Over
the ensuing years, Phil’s research leadership helped develop more
than a dozen of these biomarkers assays for the clinic. More
recently, he helped drive use of these assays in pre-clinical
laboratory animal studies. Phil Marder rose through the ranks at
Lilly to eventually lead a group of six investigators in his role
as Research Advisor. During this time, he co-authored 48
peer-reviewed scientific articles and gave podium presentations at
international conferences. He is internationally recognized for
his leadership in applying flow cytometry technology to multiple
stages of new drug development. These applications include
optimization of cell lines for monoclonal antibody secretion,
development of cell lines for neuroscience target screening,
validation of primary cell assays for anti-inflammatory platforms,
and most recently, detection of intracellular phosphoproteins for
assaying kinase inhibitor activity of targeted cancer therapies.
Phil retired from Lilly in 2007 after more than 30 years of
outstanding accomplishments including two Lilly Presidential
recognition awards. He has since begun a consulting career and
incorporated Redram Consulting, LLC in order to use his extensive
research experience for working with others in the Pharma/Biotech
and Instrument/Reagent sectors for the purpose of helping them
leverage flow cytometry technology for their own needs.
Donations in
memory of Phil can be made to the charity of Phil's choosing
http://www.voicesagainstbraincancer.org/ |